Edit RNA!
Nature 542, 494-497 (23 February 2017)
Editing and methylation at a single site by functionally interdependent activities
Mary Anne T. Rubio, Kirk W. Gaston, Katherine M. McKenney, Ian M.C. Fleming, Zdenek Paris, Patrick A. Limbach and Juan D. Alfonzo
Editing and methylation at a single site by functionally interdependent activities
Mary Anne T. Rubio, Kirk W. Gaston, Katherine M. McKenney, Ian M.C. Fleming, Zdenek Paris, Patrick A. Limbach and Juan D. Alfonzo
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Nature 542, 420-421 (23 February 2017)
Molecular biology: RNA editing packs a one-two punch
William T. Yewdell & Jayanta Chaudhuri
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| Graphic Design Acknowledgments: Juan Alfonzo, Mary Anne Rubio, Chris Trotta and Craig Foster |
How a ‘Mistake’ in a Single-Celled Organism is Actually a Rewrite Essential to Life
3 October2013
Molecular Cell Unusual Noncanonical Intron Editing Is Important for tRNA Splicing in Trypanosoma brucei
"The scientist does not study nature because it is useful;
he studies it because he delights in it, and he delights in it because it is beautiful.
If nature were not beautiful, it would not be worth knowing,
and if nature were not worth knowing, life would not be worth living."
-Jules Henri Poincare (1854-1912); French mathematician.
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| The Alfonzolab & "Thing": Cuatro de Mayo, 2013 |
OUR INTERESTS: RNA, RNA and RNA!
WHO: trypanosomes, yeast, mammals, archaebacteria
WHAT: tRNA modification, tRNA editing, tRNA transport, tRNA maturation
WHEN: preferably all the time
HOW: biochemistry, microbiology, genetics, bioinformatics, structural biology
WHERE: Dept. of Microbiology; The Center for RNA Biology
tRNA Editing and Modification...location, location, location!
Two major mechanisms import tRNAs to mitochondria: (Alfonzo & Soll 2009)
Contact People OSU Research PubMed
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| Alfonzolab: March 2012 |
